Fig. 6
From: Regulation of mitochondrial iron homeostasis by sideroflexin 2
Expression of genes related to mitochondrial metabolism is unchanged in SFXN2-KO cells. Expression of MFRN1 (a) and MFRN2 (b), which are related to mitochondrial iron import, did not differ between control and SFXN2-KO cells. c Expression of FXN, which is related to iron–sulfur cluster assembly, did not differ between control and SFXN2-KO cells. Expression of ABCB6 (d), ABCB10 (e), and ALAS2 (f), which are related to heme biosynthesis, did not differ between control and SFXN2-KO cells. n = 3 each. g Protein levels of FXN and Vdac in mitochondria isolated from control and SFXN2-KO cells were examined by Western blotting. Vdac was used as a loading control