| Taenia cecum | Carotid artery |
---|
| control | 1 μM | 10 μM | control | 1 μM | 10 μM |
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τfast-detach(sec) | 35.3 ± 3.8 | 41.1 ± 4.4 | 42.7 ± 2.6 | 139.3 ± 11.9 | 156.9 ± 23.9 | 155.4 ± 10.9 |
τslow-attach(sec) | 21.7 ± 5.1 | 27.4 ± 4.4 | 23.3 ± 4.4 | 4.0 ± 1.2 | 24.3 ± 9.7 | 5.4 ± 5.3 |
τslow-detach(sec) | 1,920.6 ± 367.1 | 1,560.3 ± 369.6 | 796.9 ± 109.5* | 1,056.4 ± 238.3 | 891.6 ± 166.4 | 435.2 ± 72.8* |
A | 0.38 ± 0.07 | 0.29 ± .05 | 0.23 ± 0.06* | 0.67 ± 0.06 | 0.69 ± 0.08 | 0.24 ± 0.16* |
- Kinetic parameters of the relaxation processes of the skinned taenia cecum and carotid artery of the guinea pig in Relaxing solution (with CTP) in the presence or absence of CC-D. Parameters of τfast-detach, τslow-attach, τslow-detach and A represent the rate constants of fast detaching, slowly attaching and slow detaching cross-bridge, and the rate of re-attachment of detached crossbridge, respectively. Values represent mean ± S.E.M. (taenia cecum n = 8, carotid artery n = 8) *P < 0.05